The Seattle Seahawks (0-1) hit the road to take on the Detroit Lions (1-0) in a cross-division Week 2 NFC matchup on Sunday. The Seahawks are looking to rebound from a 30-13 home blowout loss to the Los Angeles Rams in Week 1, while the Lions are hoping to build off their 21-20 upset win over the defending Super Bowl champion Kansas City Chiefs in the season opener. The Seahawks lead the all-time series 12-5. All-Pro safety Jamal Adams remains out for Seattle, and offensive tackle Taylor Decker is doubtful for Detroit. 

Kickoff is scheduled for 1 p.m. ET at Ford Field. Detroit is favored by 4.5 points in the latest Lions vs. Seahawks odds, and the over/under for total points scored is 47. Before making any Seahawks vs. Lions picks, you need to see the NFL predictions and betting advice from the computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2023 NFL season on an incredible 163-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 17-6 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Lions vs. Seahawks and just locked in its picks and NFL Week 2 predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for Seahawks vs. Lions:

Seahawks vs. Lions spread: Lions -4.5Seahawks vs. Lions over/under: 47 pointsSeahawks vs. Lions money line: Lions -220, Seahawks +181Seahawks vs. Lions picks: See picks at SportsLineSeahawks vs. Lions live stream: fubo (try for free)

Why the Lions can cover

The Lions were…