49ers vs. Patriots prediction, odds, line, spread, time: 2024 NFL picks, Week 4 best bets from advanced model

The defending NFC champions, the San Francisco 49ers, might be in crisis mode entering their Week 4 matchup at home against the New England Patriots. San Francisco (1-2) has been without key offensive weapons, including star running back Christian McCaffrey, and lost two consecutive road games, including to the Rams last week, 27-24. New England (1-2) fell at the Jets last Thursday, 24-3, in its most recent contest. The 49ers won the last matchup between the two teams, 33-6, in October 2020.

Kickoff from Levi’s Stadium is set for 4:05 p.m. ET. San Francisco is a 10.5-point favorite in the latest 49ers vs. Patriots odds, per SportsLine consensus, while the over/under for total points is 42. Before making any Patriots vs. 49ers picks, you need to see the NFL predictions and betting advice from the proven computer model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 4 of the 2024 NFL season on an incredible 188-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 42-22 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Patriots vs. 49ers and just locked in its picks and NFL Week 4 predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for spread, money line and over/under:

49ers vs. Patriots spread: 49ers -10.549ers vs. Patriots over/under: 42 points49ers vs. Patriots money line: 49ers -595, Patriots +43849ers vs. Patriots picks: See picks at SportsLine

Why the Patriots can cover

Can the Patriots pull another shocking road upset early…

Source link : https://www.cbssports.com/nfl/news/49ers-vs-patriots-prediction-odds-line-spread-time-2024-nfl-picks-week-4-best-bets-from-advanced-model/

Author : CBS Sports Staff

Publish date : 2024-09-29 17:05:43

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